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Previously, migraine pain was thought to result primarily from the dilation of cerebral blood vessels. However, the neurogenic theory of migraine suggests that abnormal activation of trigeminal nerve pathways is the main cause of migraine pain, while vasodilation is a secondary effect.
Although the exact mechanism of action of Lasmiditan is not fully understood, it is believed to work by selectively activating 5-HT (serotonin) receptors located in both the central and peripheral nervous system, particularly on trigeminal neurons. Activation of these receptors leads to hyperpolarization of nerve terminals and inhibition of trigeminal nerve firing, thereby reducing migraine pain.
Lasmiditan has minimal affinity for other serotonin receptor subtypes and does not significantly interact with adrenergic or dopaminergic receptors.
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ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
- ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Midita is indicated for the acute treatment of migraine attacks with or without aura in adults.
It is not intended for the prevention of migraine.
Recommended dose: 50 mg, 100 mg, or 200 mg taken orally as needed
Maximum dose: One dose in 24 hours
A second dose for the same migraine attack is not effective
Safety of treating more than 4 migraine attacks per month has not been established
May be taken with or without food
Patients must be able to wait at least 8 hours before driving or operating machinery after taking Midita
Pediatric Use: Safety and effectiveness in children have not been established
Hepatic Impairment:
- Mild to moderate impairment (Child-Pugh A or B): No dose adjustment required
- Severe impairment (Child-Pugh C): Use is not recommended
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন।
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ The most commonly reported side effects include:
- Dizziness
- Fatigue
- Paresthesia (tingling sensation)
- Sedation
✔️ Drug Interactions
CNS Depressants:
Use with caution when taken with alcohol or other CNS depressants due to the risk of sedation and cognitive impairment.
Serotonergic Drugs:
Concomitant use with SSRIs, SNRIs, TCAs, MAO inhibitors, trazodone, dextromethorphan, or herbal supplements like St. John’s Wort may increase the risk of serotonin syndrome.
Heart Rate–Lowering Drugs:
Midita may reduce heart rate. When used with medications such as propranolol, additional heart rate reduction may occur. Use caution if significant bradycardia is a concern.
P-gp and BCRP Substrates:
Midita inhibits P-gp and BCRP transporters; therefore, concomitant use with drugs that are substrates of these transporters should be avoided.
✔️ Pregnancy & Lactation
Pregnancy:
There are no adequate data on the use of Lasmiditan in pregnant women. Animal studies have shown developmental toxicity at certain exposure levels. Use only if clearly needed.
Lactation:
There is no information on Lasmiditan in human breast milk. Animal studies indicate that Lasmiditan and/or its metabolites are excreted into milk at higher concentrations than in maternal plasma. Caution is advised.
✔️ Precautions & Warnings
Driving Impairment: Patients should not drive or operate machinery for at least 8 hours after taking Midita
CNS Depression: Use cautiously with alcohol or other CNS depressants
Serotonin Syndrome: Discontinue Midita if symptoms occur
Medication Overuse Headache: Detoxification may be required in some cases
✔️ Storage:
Store below 30°C, protected from light and moisture.
Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
